NIPT technologies have been validated in singleton and twins pregnancies at high risk for trisomy 21 due to:
Ø Advanced maternal age
Ø Abnormal Ultrasound findings
Ø Suspicious serum markers for Trisomy 21,18,13
Ø Personal or family history of aneuploidy.
Ø A previous pregnancy with a chromosomal condition
Ø Received IVF treatment /Donor egg
Ø Still has general concerns about the health of the fetus